shRNA Lentivirus (self-inactivating), pH1-(SF3A2-shRNA-Seq1)(CAT#: LV-SI0560WQ)
This product is a SF3A2-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The SF3A2 gene encodes subunit 2 of the splicing factor 3a protein complex, which interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. The expression of SF3A2-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Retroviridae |
Species | Lentivirus |
Serotype | HIV-1 |
Backbone | Lenti-SIN |
Tropism | Both nondividing and dividing cells |
Insert | SF3A2-shRNA-Seq1 |
Related Target/Protein | SF3A2 |
Region | CDS |
TargetSeq | CTGGGCTCCTATGAATGCAAA |
NCBI RefSeq | NM_007165 |
Alternative Names | PRP11; SAP62; PRPF11; SF3a66 |
Titer | >1*10^10 GC/mL |
Related Diseases | Mitotic chromosome segregation |