shRNA Lentivirus (self-inactivating), pH1-(SF3A2-shRNA-Seq1)(CAT#: LV-SI0560WQ)

This product is a SF3A2-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The SF3A2 gene encodes subunit 2 of the splicing factor 3a protein complex, which interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. The expression of SF3A2-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Retroviridae
Species Lentivirus
Serotype HIV-1
Backbone Lenti-SIN
Tropism Both nondividing and dividing cells
Insert SF3A2-shRNA-Seq1
Related Target/Protein SF3A2
Region CDS
TargetSeq CTGGGCTCCTATGAATGCAAA
NCBI RefSeq NM_007165
Alternative Names PRP11; SAP62; PRPF11; SF3a66
Titer >1*10^10 GC/mL
Related Diseases Mitotic chromosome segregation
Target Gene
Gene ID 8175
Uniprot ID Q15428

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