shRNA Lentivirus (self-inactivating), pH1-(VRTN-shRNA-Seq2)(CAT#: LV-SI0602WQ)

This product is a VRTN-shRNA encoding Lentivirus, which is based on HIV-1 serotype. VRTN is required for the development of thoracic vertebrae in mammals. VRTN is a novel DNA-binding transcription factor as it localizes exclusively in the nucleus, binds to DNA on a genome-wide scale and regulates the transcription of a set of genes that harbor VRTN binding motifs. The expression of VRTN-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Retroviridae
Species Lentivirus
Serotype HIV-1
Backbone Lenti-SIN
Tropism Both nondividing and dividing cells
Insert VRTN-shRNA-Seq2
Related Target/Protein VRTN
Region CDS
TargetSeq CCAAGTTGTACCTGGAGCATT
NCBI RefSeq NM_018228
Alternative Names vertnin; C14orf115
Titer >1*10^10 GC/mL
Related Diseases Development of Thoracic Vertebrae in Mammals
Target Gene
Gene ID 55237
Uniprot ID Q9H8Y1

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