shRNA Lentivirus (self-inactivating), pU6-(SH3D19-shRNA-Seq2)(CAT#: LV-SI0277WQ)

This product is a SH3D19-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The SH3D19 gene encoded protein may be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1 by EBP, and regulation of ADAM proteins in the signaling of EGFR-ligand shedding. The expression of SH3D19-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.