shRNA Lentivirus (self-inactivating), pU6-(WDR74-shRNA-Seq1)(CAT#: LV-SI0451WQ)

This product is a WDR74-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The WDR74 gene participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL and is required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development. The expression of WDR74-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.