shRNA Adeno-associated Virus Serotype 2, p7SK-(KLHL7-shRNA-Seq1)(CAT#: AAV-SI1064WQ)
This product is a KLHL7-shRNA encoding AAV, which is based on AAV-2 serotype. The KLHL7 encoded protein may be involved in protein degradation. Mutations in this gene have been associated with retinitis pigmentosa 42. The expression of KLHL7-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Parvoviridae |
Species | Adeno-associated virus (AAV) |
Serotype | AAV-2 |
Backbone | AAV-2 |
Tropism | CNS, muscle, liver, brain, eye |
Insert | KLHL7-shRNA-Seq1 |
Related Target/Protein | KLHL7 |
Region | 3UTR |
TargetSeq | CGCAGTATCTTAGCTCTAGAT |
NCBI RefSeq | NM_018846 |
Alternative Names | CISS3; KLHL6; SBBI26 |
Titer | >1*10^10 GC/mL |
Related Diseases | Retinitis pigmentosa |