shRNA Adeno-associated Virus Serotype 2, pH1-(Pomp-shRNA-Seq2)(CAT#: AAV-SI2576WQ)
This product is a Pomp-shRNA encoding AAV, which is based on AAV-2 serotype. The protein encoded by Pomp gene is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. The expression of Pomp-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Parvoviridae |
Species | Adeno-associated virus (AAV) |
Serotype | AAV-2 |
Backbone | AAV-2 |
Tropism | CNS, muscle, liver, brain, eye |
Insert | Pomp-shRNA-Seq2 |
Related Target/Protein | Pomp |
Region | CDS |
TargetSeq | GCTCAAACCTCTCACTGGATA |
NCBI RefSeq | NM_025624 |
Alternative Names | UMP1; PRAAS2; HSPC014; C13orf12; PNAS-110 |
Titer | >1*10^10 GC/mL |
Related Diseases | KLICK syndrome |