shRNA Adeno-associated Virus Serotype 2, pU6-(C20orf43-shRNA-Seq2B)(CAT#: AAV-SI2002WQ)

This product is a C20orf43-shRNA encoding AAV, which is based on AAV-2 serotype. The C20orf43 gene may be required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication and function to facilitate fork pausing at replication fork barriers like the rDNA. The expression of C20orf43-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.