shRNA Adeno-associated Virus Serotype 2, pU6-(Psme4-shRNA-Seq4)(CAT#: AAV-SI1724WQ)

This product is a Psme4-shRNA encoding AAV, which is based on AAV-2 serotype. The protein encoded by Psme4 gene is associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during spermatogenesis and DNA damage response. The expression of Psme4-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.