Antibody Screening and Characterization

In order to understand and predict the performance and interaction of antibody leads in immunotherapy, antibody screening and characterization are critical. Our team provides high-throughput screening, as well as antibody biochemical characterization by ELISA, FACS and other image-based binding methods to ensure the identification of highly potent antibody candidates for immunoassays and immunotherapeutic studies.

We have extensive experience in antibody high-throughput screening and antibody characterization, including receptor ligand binding assays (antibody blocking effects), epitope binding assays (antibody and antigen binding assays), and immune cells assay (immunity and immunological checkpoint analysis), ADCC / CDC, cell-based proliferation and apoptosis analysis, etc.

Detailed Antibody Screening and Characterization

Key Antibody Screening

Key Antibody Characterization

Primary Screening (10,000-50,000 samples per assay)
• Screening by ELISA (protein-based)
• Screening by FACS (cell-based)
• Image-based homology assay (protein or cell-based)
Secondary screening (1,000-3,000 samples per assay)
• Cross-species and cross-family screening
• Quantitative ELISA / FACS
• Competitive ELISA

• Epitope Binding: Grouping antibodies according to the target area they recognize.
• Affinity Ranking: Relative affinity is selected by HTS.
• Cross-reactivity: Negative screening for cross-reactivity is used to guide the selection of appropriate specific clones.
• Cell-based Screening: Antibodies against cell surface antigens are the best screening in the native context.

Our Strengths

✔ Guarantee: each step is accompanied by a guarantee based on the success of the steps.
✔ A wide range of solutions: we have come up with a complete pipeline to provide you with flexible options.
✔ State-of-the-art equipment: your project deserves the best equipment in an efficient manner.

Creative Biolabs' years of expertise and propriety technologies enable us to offer a full range of services covering all screening and characterization requirements. All of these services can be seamlessly integrated with our custom Antibody Engineering services. To obtain further information, please contact us.