Short Decsription
This product is a Carbon-halide lyases-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL3-YTHDF1-FTO-ACL-phos) modification and Glycogen synthesis-mediated (TDP-43-Acetyl-CoA-ADP) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
ACL
RNA types
tRNA
Modification
ac4C
Label
phos
RNA editing
C to U
Cell Type
CD8 T Cells
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
tRNA-ac4C-METTL3-YTHDF1-FTO-ACL-phos
Substrates
Acetyl-CoA
Cofactors
ADP
Pathway
Glycogen synthesis
Epigenetic regulator
KMT2D inhibition
Metabolic alteration
Upregulating glycolysis and lipids metabolism
Targeting diseases
Lung Cancer
RNA-binding proteins
TDP-43
Metabolic Reprogramming
Glycogen synthesis-TDP-43-Acetyl-CoA-ADP

For Research Use Only | Not For Clinical Use

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