Short Decsription
This product is a D-xylulose reductase-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL3-YTHDF1-FTO-HDACs-spacer C9) modification and Gluconeogenesis-mediated (RBM9-SAM-ADP) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
HDACs
RNA types
tRNA
Modification
ac4C
Label
spacer C9
RNA editing
C to U
Cell Type
DCs
Oligonucleotide
2'-OMe (cationic lipoplex)
RNA Construction
tRNA-ac4C-METTL3-YTHDF1-FTO-HDACs-spacer C9
Substrates
SAM
Cofactors
ADP
Pathway
Gluconeogenesis
Epigenetic regulator
KDM5A overexpression
Metabolic alteration
Upregulating glycolysis
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
RBM9
Metabolic Reprogramming
Gluconeogenesis-RBM9-SAM-ADP

For Research Use Only | Not For Clinical Use

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