Short Decsription
This product is a DWARF27-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL14-YTHDF2-ALKBH5-KMTs-spacer C9) modification and TCA cycle-mediated (hnRNPs-SAM-ADP) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
KMTs
RNA types
rRNA
Modification
ac4C
Label
spacer C9
RNA editing
A to I
Cell Type
M1 macrophages
Oligonucleotide
2'-OMe (cationic lipoplex)
RNA Construction
rRNA-ac4C-METTL14-YTHDF2-ALKBH5-KMTs-spacer C9
Substrates
SAM
Cofactors
ADP
Pathway
TCA cycle
Epigenetic regulator
EZH2 deficiency
Metabolic alteration
Activating branched-chain amino acidsmetabolism
Targeting diseases
Lung Cancer
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
TCA cycle-hnRNPs-SAM-ADP

For Research Use Only | Not For Clinical Use

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