Short Decsription
This product is a Peroxidase-targeted RNA modification and metabolomics analysis tool based on the m1A (METTL14-HNRNPs-ALKBH5-ALKBH5-spacer C18) modification and Glycolysis-mediated (hnRNPs-SAM-ATP) metabolic analysis system.
RNA writers
METTL14
RNA readers
HNRNPs
RNA erasers
ALKBH5
Enzymes
ALKBH5
RNA types
tRNA
Modification
m1A
Label
spacer C18
RNA editing
A to I
Cell Type
M2 macrophages
Oligonucleotide
cET, 2'-MOE
RNA Construction
tRNA-m1A-METTL14-HNRNPs-ALKBH5-ALKBH5-spacer C18
Substrates
SAM
Cofactors
ATP
Pathway
Glycolysis
Epigenetic regulator
SMARCA4 deficiency
Metabolic alteration
Upregulating oxidative phosphorylation
Targeting diseases
Glioma
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Glycolysis-hnRNPs-SAM-ATP

For Research Use Only | Not For Clinical Use

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