HEK293-based Cytotoxicity Safety Screening Service
HEK293 Cells For Cytotoxicity Screening Studies
HEK293 cells, a widely used human embryonic kidney cell line, serve as an ideal in vitro model for initial toxicity screening due to their robust and reproducible growth characteristics. Their origin from human kidney cells makes them particularly relevant for assessing kidney-specific toxic effects. Their relevance in drug development is well-documented, providing valuable insights into the cellular responses of kidney cells to drug candidates. Creative Biolabs offers high-throughput cytotoxicity screening services that leverage the utility of HEK293 cells to assess the cytotoxicity of various compounds using cell viability assays. Our scientists assess cytotoxicity quickly and accurately, ensuring that only safe and effective drug candidates proceed through the development pipeline.
HEK293-based Cytotoxicity Safety Screening Service by Creative Biolabs
Creative Biolabs offers state-of-the-art, HEK293-based cytotoxicity screening services to screen a variety of compounds, including small molecules, peptides, proteins, antibodies, and more, facilitating broad applications in drug discovery and safety evaluation. Utilizing a homogeneous, luminescent cell viability assay, our service provides an accurate, sensitive measure of cytotoxic effects, crucial for determining the safety profile of drug candidates. This advanced screening technique allows for the simultaneous testing of a large number of compounds, vastly improving efficiency and throughput. By leveraging this high-throughput approach, researchers can rapidly accumulate reliable data, accelerating the decision-making process and ultimately expediting the journey from bench to bedside.
Our service employs cell viability assays that quantify the ATP content within HEK293 cells as an indicator of cytotoxicity. Our assay process begins with the exposure of HEK293 cells to various concentrations of the test compounds. Subsequently, the viability of these cells is assessed by measuring their ATP content, which reflects the metabolic activity and, therefore, the health of the cells. The assay is normalized and interpreted by comparing the ATP levels in treated cells to those in untreated control cells, enabling us to accurately assess the cytotoxic potential of each compound. Through this meticulous approach, Creative Biolabs ensures reliable and reproducible results, assisting clients in making informed decisions during the early stages of drug development.
Applications
Advantages
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High-Throughput Capability: Our service is designed for high-throughput screening, allowing for the simultaneous evaluation of multiple compounds, thus expediting the early-stage drug discovery process.
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Sensitive Detection: The cell viability assay employed offers high sensitivity in detecting changes in ATP levels, thereby providing accurate measures of cytotoxicity.
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Experienced Team: Our team of experts provides valuable insights and support throughout the screening process, ensuring high-quality data and interpretation.
To learn more about our HEK293-based cytotoxicity safety screening service or to discuss your specific research needs, please contact us.
For Research Use Only | Not For Clinical Use
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