HPLC-MS/MS-based Cytochrome P450 2B6 (CYP2B6) Inhibition Assessment Service
Creative Biolabs offers cutting-edge technology and expertise to accurately assess the inhibitory potential of compounds on CYP2B6, a critical enzyme involved in drug metabolism. With our customizable and reliable assays, we can help you evaluate the inhibitory effects of your compounds, prioritize lead compounds, and optimize drug development processes. Trust us to provide you with precise and efficient results to support your research and development efforts.
HPLC-MS/MS-based CYP Inhibition Assessment Platform
HPLC-MS/MS-based Cytochrome P450 2B6 (CYP2B6) Inhibition Assessment Service
CYP2B6
Our HPLC-MS/MS-based CYP2B6 inhibition assessment service offers a reliable and accurate method to evaluate the inhibitory effects of test compounds on the activity of CYP2B6. The assay utilizes high-performance liquid chromatography coupled with tandem mass spectrometry to quantitatively measure the metabolism of specific CYP2B6 substrates in the presence of test compounds.
What We Do
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Measurement of CYP2B6 enzyme activity using HPLC-MS/MS technology.
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To evaluate the potential of the sample to be tested to inhibit CYP2B6 enzyme activity.
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Determination of inhibition kinetic parameters including IC50 values.
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Delivery comprehensive reports summarizing the results of the inhibition assessments.
Key Features of Our Service
High sensitivity and specificity: Our HPLC-MS/MS platform allows for precise quantitation of CYP2B6 activity at low substrate concentrations.
Customized assay design: Creative Biolabs customizes assays to meet your specific research needs, including the use of different substrates and test compound concentrations.
Rapid turnaround time: Our experienced team can provide fast and reliable results to support your drug development efforts.
Comprehensive data analysis: Creative Biolabs provides in-depth data analysis and interpretation to help you understand the inhibition of CYP2B6 activity by the test compounds.
Confidentiality and data security: Creative Biolabs prioritizes the confidentiality of your research data and maintains strict data security protocols throughout the assay process.
Detailed Information of Our Service
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Protein Name
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Family
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Sub Family
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Uniprot Number
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Gene Name
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CYP2B6
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CYP450
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CYP2
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P20813
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CYP2B6
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Gene ID
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Gene Aliases
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Organism
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Construct Details
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Tissue
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1555
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CPB6|CYPIIB6
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Human
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Microsomes
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Liver
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Measured Response
Peak Area Response
Service Sub Type
Enzymatic
Detection Method
HPLC-MS/MS
Importance of CYP2B6 Inhibition Assessment
CYP2B6 is involved in the metabolism of a variety of drugs and can be inhibited by other drugs, leading to potential drug-drug interactions. Assessing CYP2B6 inhibition helps to predict and prevent these interactions, which can affect the efficacy and safety of the medications involved.
Inhibition of CYP2B6 can alter the pharmacokinetic profile of drugs that are substrates of this enzyme. Understanding the extent of CYP2B6 inhibition can help optimize dosing regimens and predict potential adverse effects associated with altered drug metabolism.
Inhibition of CYP2B6 can lead to the accumulation of toxic metabolites of certain drugs. Assessing CYP2B6 inhibition is crucial for evaluating the potential for drug-induced toxicity and guiding the development of safer medications.
Cooperation With Creative Biolabs
Contact Us
To learn more about our HPLC-MS/MS-based Cytochrome P450 2B6 (CYP2B6) Inhibition Assessment Service, get in touch with our team of experts now. Our scientific team is committed to providing our clients with the highest quality services to meet your specific immuno-oncology needs and help you achieve your research goals. If you are interested in this service, please contact us today and our technical team will be available around the clock to discuss how we can help you advance your drug discovery and development projects.
For Research Use Only | Not For Clinical Use
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