Short Decsription
This product is a Octanoyl-ACP-targeted RNA modification and metabolomics analysis tool based on the m6Am (METTL3-YTHDC1-ALKBH5-HDACs-spacer C18) modification and Fatty acid synthesis-mediated (hnRNPs-Lactyl-CoA-NAD+) metabolic analysis system.
Oligonucleotide
2'-MOE, GalNAc
RNA Construction
mRNAs-m6Am-METTL3-YTHDC1-ALKBH5-HDACs-spacer C18
Pathway
Fatty acid synthesis
Epigenetic regulator
SMARCA4 overexpression
Metabolic alteration
Upregulating fatty acids synthesis
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Fatty acid synthesis-hnRNPs-Lactyl-CoA-NAD+