Short Decsription
Ensure efficient CD22 detection with this all-inclusive IHC kit, pre-formulated with every reagent needed from antigen retrieval to slide completion.
Description
CD22, also known as Siglec-2 or BL-CAM, is a B-cell-restricted, 130-140 kDa type I transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. CD22 is developmentally regulated and functions as an inhibitory receptor for B-cell receptor (BCR) signaling. It binds preferentially to alpha-2,6-linked sialic acid and mediates B-cell interactions, playing a key role in activation and differentiation of B-cells.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Analytical Method
Immunohistochemistry