As an experienced CRO in the field of cancer immunotherapy discovery and development, Creative Biolabs has
developed into the best trusted partner who is fully competent and dedicated to providing a suite of
standalone or integrated services throughout the life cycle of drug discovery and development, including discovery, biologics testing, development, preclinical testing, cGMP Manufacturing, as well as regulatory
services.
Background
Drug discovery and development pathway is a long journey, and complications and inefficiencies at the late
stage can create costly delays. Therefore, safety and efficacy profiles assessments of drug candidates prior
to clinical trials are critical stages to avoid unnecessary loss. Preclinical testing in animal models can
help to foreseen potential risks of drug candidates before exposure to humans, and hence reduce the cost for
pharmaceutical industries and help to make the appropriate choice. Now immunotherapy has emerged as a major
approach to treat malignancies including small chemical molecules and biologics drugs, we are dedicated to
serving preclinical testing for immunotherapy potential drugs.
Fig.1 Schematic diagram of our end-to-end drug discovery and development services.
Introduction of Preclinical Testing Services
Creative Biolabs is dedicated to providing flexible solutions and accelerated timelines for our clients who
care about making a difference for immuno-oncology. Our experienced scientists and skillful technicians
execute individual studies via state-of-the-art technologies in a global worldwide network of
facilities.
Furthermore, custom preclinical testing studies which are designed to fit client’s goals are also available
in Creative Biolabs. Our regulatory experts ensure that all preclinical testing services are in compliance
with worldwide standards for quality and regulations to smooth the path to market. Here are our provided
services for your quick check but not limited to these.
Creative Biolabs is committed to conducting non-GLP and GLP efficacy in vivo studies to meet the
needs of our
clients. We offer efficacy models including cell line derived xenograft models, humanized models,
immuno-deficient mice, syngeneic models and chemical-induced cancer model to support different oncology
areas that incorporate biomarkers and outcome measures to enable greater success in the clinic. The
appropriate model will be designed to meet their scientific objectives, and custom studies will be designed
and custom protocols and statements of work (SOWs) will be developed to meet quality assurance guidelines.
Our pharmacology program helps clients to accelerate the development of their cancer immunotherapy candidates via investigating the potential actions of compounds or biologics on physiological functions under
exposure
in the therapeutic range and above. We offer a comprehensive, harmonized, global pharmacology program in
compliance with the ICH guidelines.
Empowered by our board-certified toxicologists, veterinary surgeons, veterinary pathologists, regulatory
specialists and support technicians, Creative Biolabs has designed and performed toxicology programs over
decades. These programs cover a wide range of animal models and employ various routes of administration, and
evaluate acute through chronic toxicity and carcinogenicity.
Purpose of Our Immuno-Oncology Preclinical Animal Testing
Highlight Features of Our Services
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✔ Around 100 studies completed every year;
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✔ With a globally advanced platform empowered with various technologies;
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✔ An integrated and multi-disciplinary approach.
Creative Biolabs is committed to end-to-end immuno-oncology preclinical animal testing be compliance with
ICH guidelines to meet regulatory requirements. Our experienced team helps clients to avoid roadblocks,
anticipate challenges, and expedite preclinical drug development with a wide array of services and expert
guidance through this important stage. If you want to have a further communication or any other requests,
please feel free to contact us.
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