HSP70-expressing Oncolytic Herpes Simplex Virus 2 (ΔRL), hTERT-HSP70(Cat#: CyOV-0326XY)

This product is a HSP70 expressing oncolytic herpes simplex virus, which is based on HSV-2 with RL deleted. The deletion lies entirely within the sequences deleted in JH2604 in which only 850 bp are removed from the RL. This product can be used in oncolytic virotherapy research and further recombinant HSV construction.

Specifications

Family Herpesviridae
Species Herpes simplex virus
Serotype Herpes simplex virus 2
Backbone HSV-2 (ΔRL)
Backbone Background Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known as human herpesvirus 1 and 2 (HHV-1 and HHV-2), are two members of the human Herpesviridae family, a set of viruses that produce viral infections in the majority of humans. Modified Herpes simplex virus is considered as a potential therapy for cancer and has been extensively clinically tested to assess its oncolytic ability.
Gene Modification ΔRL
Promoter hTERT
Transgene HSP70
Type of Transgene Cytokine
Related Target/Protein Heat shock protein 70
Capsid Modification None
Titer >1*10^8 PFU
Related Diseases Tumor

Transgene

Alternative Names HSP70, APG-2, HEL-S-5a, HS24/P52, HSPH2, RY, hsp70, hsp70RY, heat shock protein family A (Hsp70) member 4
Gene ID 3308

Information

Introduction The 70 kilodalton heat shock proteins (Hsp70s or DnaK) are a family of conserved ubiquitously expressed heat shock proteins. Proteins with similar structure exist in virtually all living organisms. The Hsp70s are an important part of the cell's machinery for protein folding, and help to protect cells from stress.

Customer Reviews and Q&As

There are currently no customer reviews or questions for HSP70-expressing Oncolytic Herpes Simplex Virus 2 (ΔRL), hTERT-HSP70 (CyOV-0326XY). Click the button below to contact us or submit your feedback about this product.

All products and services are for Research Use Only. Not For Clinical Use.

Other products

PRODUCTS

Online Inquiry