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MC-Val-Cit-PAB-carfilzomib (CAT#: ADC-S-066)

Linker-Toxin SET, this set is made by carfilzomib conjugated to the lysosomally cleavable MC-vc-PAB linker. Carfilzomib is an irreversible proteasome inhibitor, which can irreversibly bind to and inhibit the chymotrypsin-like activity of the 20S catalytic core subunit of the proteasome and lead to cell cycle arrest, apoptosis, and inhibit tumor growth.

  • Product Information
  • CAS NO
  • 2055896-83-6
  • Description
  • Linker-Toxin SET, this set is made by carfilzomib conjugated to the lysosomally cleavable MC-vc-PAB linker. Carfilzomib is an irreversible proteasome inhibitor, which can irreversibly bind to and inhibit the chymotrypsin-like activity of the 20S catalytic core subunit of the proteasome and lead to cell cycle arrest, apoptosis, and inhibit tumor growth.
  • Molecular Weight
  • 1275.56
  • Purity
  • 95%

For Research Use Only. NOT FOR CLINICAL USE.

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