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- Vorsetuzumab-iFluor 750
Vorsetuzumab-iFluor 750 (CAT#: ADC-FL-893)
This product is comprised of an anti-CD70 monoclonal antibody (Vorsetuzumab) labeled with iFluor 750. iFluor 750 is a near-IR-fluorescent dye and it's excitation/emission is 749/775 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- CD70
- Alternative Names
- CD70; CD70 molecule; CD27LG, TNFSF7, tumor necrosis factor (ligand) superfamily, member 7; CD70 antigen; CD27L; CD27-L; CD27 ligand; Ki-24 antigen; surface antigen CD70; tumor necrosis factor ligand superfamily member 7; tumor necrosis factor (ligand) superfamily, member 7; CD27LG; TNFSF7;
- Overview
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
- Overview
- Humanized Anti-CD70 IgG1-kappa antibody, Vorsetuzumab
- Generic name
- Vorsetuzumab
- Species Reactivity
- Human
- Name
- iFluor 750
- Color
- Near-IR
- Excitation⁄Emission (nm)
- 749/775
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-452 | Anti-CD70 (clone 1F6)-Mc-MMAF ADC | Mc (maleimidocaproyl) | MMAF (Monomethyl auristatin F) |
| ADC-W-471 | Anti-CD70-VC-MED-2460-ADC | VC (valine-citrulline) | MED-2460 |
| ADC-W-955 | Anti-CD70 (Vorsetuzumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-954 | Anti-CD70 (Vorsetuzumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-376 | Anti-CD70 (clone h1F6)-β-glucuronide-doxorubicin ADC | β-glucuronide linker | doxorubicin |
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