Anti-disease-specific Target Antibody Introduction

A target is a protein or enzyme in biology that has a specific effect, or it can be a specific cell or molecule. They can be acted upon by a drug, antibody, or other external stimulus to interfere with the function of a receptor and regulate the activity of a cell. Or they affect the action between cells and molecules in a specific way. Target-based therapies can be developed for specific diseases, pathogens, or disease processes. Creative Biolabs is an expert in developing anti-disease-specific target antibodies. Through our phage display platform and hybridoma platform, we can provide you with custom antibody production services.

Anti-tumor-specific Target Antibody

Tumor-specific targets are a class of proteins specifically expressed in tumor cells, but rather than normal cells, and therefore heir specific expression can be specifically identified by monoclonal antibodies, which can thereby selectively kill tumor cells. There are varieties of antibody drugs against tumor-specific targets, which also play a good therapeutic role. We take some tumor-specific targets as examples to explore the way anti-tumor-specific target antibodies work. For example, anti-HER2 antibodies can inhibit tumor cell growth by blocking the dimerization of HER2 and receptors and can also trigger antibody-dependent cytotoxic effects to kill tumor cells. Anti-EGFR antibodies can inhibit the use of this pathway by tumor cells to trigger vascular regeneration, tumor metastasis, and thus inhibit tumor growth. Anti-c-MET antibodies are designed to inhibit tumor cells to proliferate, metastasize, or invade by downregulating c-MET. Anti-CD20 antibodies reduce B cell activity by binding to CD20 on the surface of B cells, subsequently initiating immune responses through complement-dependent cytotoxicity, antibody-dependent cytotoxicity, apoptosis, and direct growth inhibition. Ultimately, these antibodies facilitate the removal of B cells. The effects of these anti-tumor specific target antibodies show that anti-tumor specific target antibodies can inhibit tumor growth and progression by blocking or inhibiting key aspects of the tumor pathology.

Anti-autoimmune-disease-specific Target Antibody Assays

Autoimmune diseases occur when the immune system fails to distinguish between self and non-self substances, leading to an attack on the body's own tissues. The main goal of autoimmune disease treatment is to alleviate symptomatic features and control disease progression. TNF-α stands out as the most important target, which is mainly produced by activated macrophages, T lymphocytes, and NK cells and plays an important role in the early stages of the inflammatory immune response through the downstream TNFR1 and TNFR2 signaling pathways. Anti-TNF-α antibody drugs have an important therapeutic role in targeting rheumatoid arthritis, inflammatory bowel disease, and many other autoimmune diseases. Interleukins (ILs) are another important class of autoimmune disease targets. Common IL targets include IL-1, IL-2, IL-6, IL-7, IL-17A, IL-12, and IL-23. IL targets regulate autoimmune diseases by participating in the inflammatory process and regulating the production of immune cells. In general, anti-autoimmune disease-specific target antibodies are used to treat autoimmune diseases by modulating inflammatory and immune responses.

More Details on Anti-Membrane Protein Antibody

Anti-disease-specific target antibodies have been shown to have significant therapeutic effects in many diseases. Based on our extensive hands-on experience, Creative Biolabs would be pleased to share our knowledge and experience related to anti-disease-specific target antibodies with you to help your research run smoothly.

All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.

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