shRNA Adenovirus Serotype 5 (ΔE1/E3), p7SK-(Bex2-shRNA-Seq1)(CAT#: AdV-SI3938WQ)
This product is a Bex2-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The Bex2 gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. The expression of Bex2-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | AdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Modification | ΔE1/E3 |
Insert | Bex2-shRNA-Seq1 |
Related Target/Protein | Bex2 |
Region | 3UTR |
TargetSeq | GTTTGTGATGTACTGTTGTAA |
NCBI RefSeq | NM_009749 |
Alternative Names | BEX1; DJ79P11.1 |
Titer | >1*10^10 GC/mL |
Related Diseases | Breast cancer |