shRNA Adenovirus Serotype 5 (ΔE1/E3), p7SK-(Gramd1a-shRNA-Seq1)(CAT#: AdV-SI3914WQ)

This product is a Gramd1a-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The protein encoded by Gramd1a gene is cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER). The expression of Gramd1a-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype AdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Modification ΔE1/E3
Insert Gramd1a-shRNA-Seq1
Related Target/Protein Gramd1a
Region CDS
TargetSeq CGAAGATTATTTCCACCACCT
NCBI RefSeq NM_027898
Titer >1*10^10 GC/mL
Related Diseases Cancer
Target Gene
Gene ID 57655
Uniprot ID Q96CP6

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