shRNA Adenovirus Serotype 5 (ΔE1/E3), p7SK-(KLHL7-shRNA-Seq2)(CAT#: AdV-SI1065WQ)
This product is a KLHL7-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The KLHL7 encoded protein may be involved in protein degradation. Mutations in this gene have been associated with retinitis pigmentosa 42. The expression of KLHL7-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | HAdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Insert | KLHL7-shRNA-Seq2 |
Related Target/Protein | KLHL7 |
Region | CDS |
TargetSeq | GAACTGAAAGCTGGCACACAA |
NCBI RefSeq | NM_018846 |
Alternative Names | CISS3; KLHL6; SBBI26 |
Titer | >1*10^10 GC/mL |
Related Diseases | Retinitis pigmentosa |