shRNA Adenovirus Serotype 5 (ΔE1/E3), p7SK-(LGI4-shRNA-Seq2)(CAT#: AdV-SI1094WQ)
This product is a LGI4-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The LGI4 gene encoded protein is component of Schwann cell signaling pathway(s) that controls axon segregation and myelin formation (By similarity). The expression of LGI4-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | HAdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Insert | LGI4-shRNA-Seq2 |
Related Target/Protein | LGI4 |
Region | CDS |
TargetSeq | GATCTACCAGCATCACGAGAT |
NCBI RefSeq | NM_139284 |
Alternative Names | LGIL3; AMCNMY |
Titer | >1*10^10 GC/mL |
Related Diseases | Neurological diseases |