shRNA Adenovirus Serotype 5 (ΔE1/E3), p7SK-(SH3BP5-shRNA-Seq2)(CAT#: AdV-SI1439WQ)
This product is a SH3BP5-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The SH3BP5 gene functions as guanine nucleotide exchange factor (GEF) with specificity for RAB11A and RAB25. The expression of SH3BP5-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | HAdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Insert | SH3BP5-shRNA-Seq2 |
Related Target/Protein | SH3BP5 |
Region | CDS |
TargetSeq | CAAAGCTGTGGAAGACTCCAA |
NCBI RefSeq | NM_004844 |
Alternative Names | SAB; SH3BP-5 |
Titer | >1*10^10 GC/mL |
Related Diseases | Acute Liver Failure |