shRNA Adenovirus Serotype 5 (ΔE1/E3), p7SK-(TTC1-shRNA-Seq2)(CAT#: AdV-SI1147WQ)
This product is a TTC1-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The TTC1 gene encoded protein plays a role in protein-protein interactions, and binds to the Galpha subunit of G protein-coupled receptors to activate the Ras signaling pathway. The expression of TTC1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | HAdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Insert | TTC1-shRNA-Seq2 |
Related Target/Protein | TTC1 |
Region | 3UTR |
TargetSeq | CCTGATGTAATGAACCTAATT |
NCBI RefSeq | NM_003314 |
Alternative Names | TPR1 |
Titer | >1*10^10 GC/mL |
Related Diseases | Medullary Thyroid Cancer |