shRNA Adenovirus Serotype 5 (ΔE1/E3), p7SK-(TTC18-shRNA-Seq2)(CAT#: AdV-SI1115WQ)
This product is a TTC18-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The TTC18 gene ecoded protein is a novel axoneme-binding protein that localizes at the base of the outer dynein arm and regulates ciliary motility. The expression of TTC18-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | HAdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Insert | TTC18-shRNA-Seq2 |
Related Target/Protein | TTC18 |
Region | CDS |
TargetSeq | CCTCCTAACTGAAGACAACAT |
NCBI RefSeq | NM_145170 |
Alternative Names | CFAP70 |
Titer | >1*10^10 GC/mL |
Related Diseases | Outer dynein arm (ODA) |