shRNA Adenovirus Serotype 5 (ΔE1/E3), pH1-(EWSR1-shRNA-Seq2)(CAT#: AdV-SI0536WQ)
This product is a EWSR1-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The EWSR1 gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The expression of EWSR1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | HAdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Insert | EWSR1-shRNA-Seq2 |
Related Target/Protein | EWSR1 |
Region | CDS |
TargetSeq | CAACAAAGCTATGGAACCTAT |
NCBI RefSeq | NM_005243 |
Alternative Names | EWS; EWS-FLI1; bK984G1.4 |
Titer | >1*10^10 GC/mL |
Related Diseases | Ewing sarcoma as well as neuroectodermal tumors |