shRNA Adenovirus Serotype 5 (ΔE1/E3), pH1-(OR52E5-shRNA-Seq4)(CAT#: AdV-SI2451WQ)

This product is a OR52E5-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The OR52E5 gene encodes a olfactory receptor protein that interacts with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The expression of OR52E5-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype AdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Modification ΔE1/E3
Insert OR52E5-shRNA-Seq4
Related Target/Protein OR52E5
Region CDS
TargetSeq CCTTCTTTGCAGTGTATCTAA
NCBI RefSeq XM_372369
Alternative Names OR11-56
Titer >1*10^10 GC/mL
Related Diseases Olfactory dysfunction
Target Gene
Gene ID 390082
Uniprot ID Q8NH55

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