shRNA Adenovirus Serotype 5 (ΔE1/E3), pH1-(Pomp-shRNA-Seq1)(CAT#: AdV-SI2575WQ)
This product is a Pomp-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The protein encoded by Pomp gene is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. The expression of Pomp-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | AdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Modification | ΔE1/E3 |
Insert | Pomp-shRNA-Seq1 |
Related Target/Protein | Pomp |
Region | CDS |
TargetSeq | CAAACCTCTCACTGGATATTT |
NCBI RefSeq | NM_025624 |
Alternative Names | UMP1; PRAAS2; HSPC014; C13orf12; PNAS-110 |
Titer | >1*10^10 GC/mL |
Related Diseases | KLICK syndrome |