shRNA Adenovirus Serotype 5 (ΔE1/E3), pH1-(Zpbp-shRNA-Seq4)(CAT#: AdV-SI2809WQ)
This product is a Zpbp-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. ZPBP is one of several proteins that are thought to participate in secondary binding between acrosome-reacted sperm and the egg-specific extracellular matrix, the zona pellucida. The expression of Zpbp-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | AdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Modification | ΔE1/E3 |
Insert | Zpbp-shRNA-Seq4 |
Related Target/Protein | Zpbp |
Region | CDS |
TargetSeq | CCTGTGAAATATCCTTGATTA |
NCBI RefSeq | NM_015785 |
Alternative Names | ZPBP1 |
Titer | >1*10^10 GC/mL |
Related Diseases | Infertility |