shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(Adipor1-shRNA-Seq1)(CAT#: AdV-SI1833WQ)

This product is a Adipor1-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The Adipor1 gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. The expression of Adipor1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype AdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Modification ΔE1/E3
Insert Adipor1-shRNA-Seq1
Related Target/Protein Adipor1
Region CDS
TargetSeq GACAACGACTACCTGCTACAT
NCBI RefSeq NM_028320
Alternative Names CGI45; PAQR1; ACDCR1; CGI-45; TESBP1A
Titer >1*10^10 GC/mL
Related Diseases Obesity; Diabetes
Target Gene
Gene ID 51094
Uniprot ID Q96A54

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