shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(Atat1-shRNA-Seq1)(CAT#: AdV-SI2326WQ)
This product is a Atat1-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The Atat1 gene encodes a protein that localizes to clathrin-coated pits, where it acetylates alpha tubulin on lysine 40. The expression of Atat1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | AdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Modification | ΔE1/E3 |
Insert | Atat1-shRNA-Seq1 |
Related Target/Protein | Atat1 |
Region | CDS |
TargetSeq | CCCACAGGTGAACAACTTTGT |
NCBI RefSeq | NM_028476 |
Alternative Names | TAT; MEC17; C6orf134; Nbla00487; alpha-TAT; alpha-TAT1 |
Titer | >1*10^10 GC/mL |