shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(Sash3-shRNA-Seq1)(CAT#: AdV-SI2246WQ)

This product is a Sash3-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The protein encoded by Sash3 gene contains a Src homology-3 (SH3) domain and a sterile alpha motif (SAM), both of which are found in proteins involved in cell signaling. This protein may function as a signaling adapter protein in lymphocytes. The expression of Sash3-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.