shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(TMEM156-shRNA-Seq2)(CAT#: AdV-SI0160WQ)
This product is a TMEM156-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. TMEM156 is expressed in several tissues including ascites, bone marrow, salivary glands, and vascular to name a few. It should be noted this gene is not ubiquitously expressed, but is still evident in many tissues. This gene is predominately expressed in adults but there is a bit of expression in fetuses. The expression of TMEM156-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | HAdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Insert | TMEM156-shRNA-Seq2 |
Related Target/Protein | TMEM156 |
Region | CDS |
TargetSeq | GTGGCAGAGTCATAGAGACAA |
NCBI RefSeq | NM_024943 |
Titer | >1*10^10 GC/mL |
Related Diseases | Breast cancer, liver cancer and prostate cancer |