shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(Tmem26-shRNA-Seq1)(CAT#: AdV-SI2212WQ)
This product is a Tmem26-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The Tmem26 gene encodes a protein containing multiple transmembrane helices. It is a selective surface protein marker of brite/beige adipocytes, which may coexist with classical brown adipocytes in brown adipose tissue. The expression of Tmem26-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
---|---|
Family | Adenoviridae |
Species | Adenovirus |
Serotype | AdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Modification | ΔE1/E3 |
Insert | Tmem26-shRNA-Seq1 |
Related Target/Protein | Tmem26 |
Region | CDS |
TargetSeq | CAGAGGCTTTGTCGACAATTT |
NCBI RefSeq | NM_177794 |
Titer | >1*10^10 GC/mL |