shRNA Lentivirus (self-inactivating), p7SK-(Psme4-shRNA-Seq4)(CAT#: LV-SI3424WQ)

This product is a Psme4-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The protein encoded by Psme4 gene is associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during spermatogenesis and DNA damage response. The expression of Psme4-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Retroviridae
Species Lentivirus
Serotype HIV-1
Backbone Lenti-SIN
Tropism Both nondividing and dividing cells
Insert Psme4-shRNA-Seq4
Related Target/Protein Psme4
Region 3UTR
TargetSeq CTAGTACTATCATGGTATTAT
NCBI RefSeq NM_134013
Alternative Names PA200
Titer >1*10^10 GC/mL
Related Diseases Infertility
Target Gene
Gene ID 23198
Uniprot ID Q14997

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