shRNA Lentivirus (self-inactivating), pH1-(APBA3-shRNA-Seq2)(CAT#: LV-SI0813WQ)
This product is a APBA3-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The protein encoded by APBA3 gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. The expression of APBA3-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Retroviridae |
Species | Lentivirus |
Serotype | HIV-1 |
Backbone | Lenti-SIN |
Tropism | Both nondividing and dividing cells |
Insert | APBA3-shRNA-Seq2 |
Related Target/Protein | APBA3 |
Region | CDS |
TargetSeq | GTCGGATGGAACTTGATGAGT |
NCBI RefSeq | NM_004886 |
Alternative Names | X11L2; mint3; MGC:15815 |
Titer | >1*10^10 GC/mL |
Related Diseases | Alzheimer's disease |