shRNA Lentivirus (self-inactivating), pH1-(Tmem146-shRNA-Seq4)(CAT#: LV-SI2829WQ)

This product is a Tmem146-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The Tmem146 gene encodes auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. The expression of Tmem146-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Retroviridae
Species Lentivirus
Serotype HIV-1
Backbone Lenti-SIN
Tropism Both nondividing and dividing cells
Insert Tmem146-shRNA-Seq4
Related Target/Protein Tmem146
Region CDS
TargetSeq CTCTAAGTACAAACTGGATAT
NCBI RefSeq NM_175350
Alternative Names CATSPERD
Titer >1*10^10 GC/mL
Related Diseases Infertility
Target Gene
Gene ID 257062
Uniprot ID Q86XM0

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