shRNA Lentivirus (self-inactivating), pU6-(Ctu2-shRNA-Seq1)(CAT#: LV-SI1788WQ)
This product is a Ctu2-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The Ctu2 gene a protein which is involved in the post-transcriptional modification of transfer RNAs (tRNAs) and plays a role in thiolation of uridine residue present at the wobble position in a subset of tRNAs, resulting in enhanced codon reading accuracy. The expression of Ctu2-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Retroviridae |
Species | Lentivirus |
Serotype | HIV-1 |
Backbone | Lenti-SIN |
Tropism | Both nondividing and dividing cells |
Insert | Ctu2-shRNA-Seq1 |
Related Target/Protein | Ctu2 |
Region | CDS |
TargetSeq | CCTTCTACAACCACCTGTTTA |
NCBI RefSeq | NM_153775 |
Alternative Names | MFRG; NCS2; UPF0432; C16orf84 |
Titer | >1*10^10 GC/mL |