shRNA Lentivirus (self-inactivating), pU6-(JMJD8-shRNA-Seq2)(CAT#: LV-SI0154WQ)

This product is a JMJD8-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The JMJD8 gene functions as a positive regulator of TNF-induced NF-kappa-B signaling and regulates angiogenesis and cellular metabolism through interaction with PKM. The expression of JMJD8-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.