shRNA Adeno-associated Virus Serotype 2, p7SK-(C8orf4-shRNA-Seq1)(CAT#: AAV-SI1063WQ)
This product is a C8orf4-shRNA encoding AAV, which is based on AAV-2 serotype. The C8orf4 gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. The expression of C8orf4-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Parvoviridae |
Species | Adeno-associated virus (AAV) |
Serotype | AAV-2 |
Backbone | AAV-2 |
Tropism | CNS, muscle, liver, brain, eye |
Insert | C8orf4-shRNA-Seq1 |
Related Target/Protein | C8orf4 |
Region | CDS |
TargetSeq | GAGACAAGAAAGCAGAGGAGA |
NCBI RefSeq | NM_020130 |
Alternative Names | TC1; TC-1; TCIM |
Titer | >1*10^10 GC/mL |
Related Diseases | Thyroid cancer, breast cancer and hematological malignancies |