shRNA Adeno-associated Virus Serotype 2, p7SK-(Erc1-shRNA-Seq1)(CAT#: AAV-SI4036WQ)
This product is a Erc1-shRNA encoding AAV, which is based on AAV-2 serotype. The protein encoded by Erc1 gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. The expression of Erc1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Parvoviridae |
Species | Adeno-associated virus (AAV) |
Serotype | AAV-2 |
Backbone | AAV-2 |
Tropism | CNS, muscle, liver, brain, eye |
Insert | Erc1-shRNA-Seq1 |
Related Target/Protein | Erc1 |
Region | CDS |
TargetSeq | GCAGATAAAGAACGGACGATT |
NCBI RefSeq | NM_053204 |
Alternative Names | ELKS; Cast2; ERC-1; RAB6IP2 |
Titer | >1*10^10 GC/mL |
Related Diseases | Thyroid papillary carcinoma |