shRNA Adeno-associated Virus Serotype 2, p7SK-(TDRD7-shRNA-Seq2)(CAT#: AAV-SI1349WQ)

This product is a TDRD7-shRNA encoding AAV, which is based on AAV-2 serotype. The protein encoded by TDRD7 gene belongs to the Tudor family of proteins. This protein contains conserved Tudor domains and LOTUS domains. It is a component of RNA granules, which function in RNA processing. Mutations in this gene have been associated with cataract formation in mouse and human. The expression of TDRD7-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.