shRNA Adeno-associated Virus Serotype 2, pH1-(Rtn4ip1-shRNA-Seq1)(CAT#: AAV-SI3102WQ)
This product is a Rtn4ip1-shRNA encoding AAV, which is based on AAV-2 serotype. The Rtn4ip1 gene encodes a mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. The expression of Rtn4ip1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Parvoviridae |
Species | Adeno-associated virus (AAV) |
Serotype | AAV-2 |
Backbone | AAV-2 |
Tropism | CNS, muscle, liver, brain, eye |
Insert | Rtn4ip1-shRNA-Seq1 |
Related Target/Protein | Rtn4ip1 |
Region | CDS |
TargetSeq | GAACATGATGTTACCTATCAT |
NCBI RefSeq | NM_130892 |
Alternative Names | NIMP; OPA10 |
Titer | >1*10^10 GC/mL |
Related Diseases | Optic atrophy |