shRNA Adeno-associated Virus Serotype 2, pU6-(Ammecr1-shRNA-Seq1)(CAT#: AAV-SI2301WQ)
This product is a Ammecr1-shRNA encoding AAV, which is based on AAV-2 serotype. Submicroscopic deletion of the Ammecr1 may result in a contiguous gene deletion syndrome, the AMME complex. The expression of Ammecr1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Parvoviridae |
Species | Adeno-associated virus (AAV) |
Serotype | AAV-2 |
Backbone | AAV-2 |
Tropism | CNS, muscle, liver, brain, eye |
Insert | Ammecr1-shRNA-Seq1 |
Related Target/Protein | Ammecr1 |
Region | 3UTR |
TargetSeq | GCCTCATGTTATAGAACAATT |
NCBI RefSeq | NM_019496 |
Alternative Names | MFHIEN; AMMERC1 |
Titer | >1*10^10 GC/mL |
Related Diseases | Alport syndrome, mental retardation, midface hypoplasia, and elliptocytosis |