shRNA Adeno-associated Virus Serotype 2, pU6-(APBA3-shRNA-Seq3)(CAT#: AAV-SI0313WQ)
This product is a APBA3-shRNA encoding AAV, which is based on AAV-2 serotype. The protein encoded by APBA3 gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. The expression of APBA3-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Parvoviridae |
| Species | Adeno-associated virus (AAV) |
| Serotype | AAV-2 |
| Backbone | AAV-2 |
| Tropism | CNS, muscle, liver, brain, eye |
| Insert | APBA3-shRNA-Seq3 |
| Related Target/Protein | APBA3 |
| Region | CDS |
| TargetSeq | CACCAAGAGGATCAAGGTCTT |
| NCBI RefSeq | NM_004886 |
| Alternative Names | X11L2; mint3; MGC:15815 |
| Titer | >1*10^10 GC/mL |
| Related Diseases | Alzheimer's disease |
