shRNA Adeno-associated Virus Serotype 2, pU6-(C12orf32-shRNA-Seq1)(CAT#: AAV-SI0398WQ)
This product is a C12orf32-shRNA encoding AAV, which is based on AAV-2 serotype. The C12orf32 gene plays a role in DNA damage response (DDR) signaling upon genotoxic stresses such as ionizing radiation (IR) during the S phase. The expression of C12orf32-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Parvoviridae |
| Species | Adeno-associated virus (AAV) |
| Serotype | AAV-2 |
| Backbone | AAV-2 |
| Tropism | CNS, muscle, liver, brain, eye |
| Insert | C12orf32-shRNA-Seq1 |
| Related Target/Protein | C12orf32 |
| Region | CDS |
| TargetSeq | GAAGCTGAGCAGAAGCCAATT |
| NCBI RefSeq | NM_031465 |
| Alternative Names | RHINO; RHNO1; HKMT1188 |
| Titer | >1*10^10 GC/mL |
| Related Diseases | DNA damage response (DDR) |
